Stacking Ipamorelin and CJC-1295: The GH Releaser Combo
The ipamorelin + CJC-1295 stack is the second most common in the peptide space (after BPC-157 + TB-500). The two compounds complement each other: CJC-1295 is a GHRH analog (growth hormone releasing hormone), ipamorelin is a GHRP (growth hormone releasing peptide). Together they produce a stronger GH pulse than either alone.
The protocol
Two variants depending on the CJC-1295 form:
CJC-1295 without DAC + ipamorelin
- Both 100-300 mcg, 2-3x daily, subcutaneous
- Same syringe (compatible)
- Empty stomach for best GH response
- Cycle: 8-12 weeks on, 4 weeks off
CJC-1295 with DAC (CJC-1295-DAC) + ipamorelin
- CJC-1295-DAC: 1-2 mg once weekly
- Ipamorelin: 100-300 mcg, 2-3x daily as above
- The DAC version has a long half-life (~8 days) so dosing schedule is decoupled
Tracking the stack
The complication: ipamorelin is multi-daily, CJC-1295 (no DAC) is also multi-daily, but CJC-1295-DAC is once weekly. If you're running the DAC version, you have asymmetric dose schedules to track.
Peptra handles both compounds independently. Each has its own dose log, schedule, and cycle. The combined view shows when both were dosed, useful for correlating subjective sleep/recovery markers.
What to track
- Sleep quality — GH secretagogues most reliably affect deep sleep. Wearable data (Oura, Whoop) plus subjective scoring.
- Recovery — perceived between training sessions
- Body composition if relevant — weight + circumference, not daily
- Side effects — flushing, water retention, tingling are reported but uncommon
Cycle endings
GH secretagogues are cycled to preserve receptor sensitivity. After 8-12 weeks, take 4 weeks off. Repeat 2-3 times per year if it suits your goals.